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5′-Deoxy-5′-methylthioadenosine phosphorylase—III: Role of the enzyme in the metabolism and action of 5′-halogenated adenosine analogs

✍ Scribed by Todd M. Savarese; Chu Shih-Hsi; Chu Ming-Yu; Robert E. Parks Jr.


Book ID
115777995
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
807 KB
Volume
34
Category
Article
ISSN
0006-2952

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AbstractÐFrom adenosine 1, 2 H -deoxyadenosine 3 and 3 H -deoxyadenosine 5 all the acetates were prepared by lipase-catalyzed reactions. Only the acetates with free 5 H -hydroxy group were deaminated by adenosine deaminase (ADA), con®rming the crucial role of 5 H -OH for the enzyme activity.