✦ LIBER ✦

5-Chloro- N -(4-methoxy-3-piperazin-1-yl- phenyl)-3-methyl-2-benzothiophenesulfon- amide (SB-271046): A Potent, Selective, and Orally Bioavailable 5-HT 6 Receptor Antagonist

✍ Scribed by Bromidge, Steven M.; Brown, Anthony M.; Clarke, Stephen E.; Dodgson, Kathy; Gager, Tracey; Grassam, Helen L.; Jeffrey, Phil M.; Joiner, Graham F.; King, Frank D.; Middlemiss, Derek N.; Moss, Stephen F.; Newman, Helen; Riley, Graham; Routledge, Carol; Wyman, Paul

Book ID: 127141349
Publisher: American Chemical Society
Year: 1999
Tongue: English
Weight: 82 KB
Volume: 42
Category: Article
ISSN: 0022-2623
DOI: 10.1021/jm980532e

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

SB-616234-A (1-[6-(cis-3,5-dimethylpiper

SB-616234-A (1-[6-(cis-3,5-dimethylpiperazin-1-yl)-2,3-dihydro-5-methoxyindol-1-yl]-1-[2′methyl-4′-(5-methyl-1,2,3-oxadiazol-3-yl)biphenyl-4-yl]methanone hydrochloride): A novel, potent and selective 5-HT1B receptor antagonist

✍ Claire Scott; Christopher J. Langmead; Kirsten L. Clarke; Paul Wyman; Paul W. Sm 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 244 KB

ChemInform Abstract: Phenyl Benzenesulfo

ChemInform Abstract: Phenyl Benzenesulfonamides Are Novel and Selective 5-HT6 Antagonists: Identification of N-(2,5-Dibromo-3-fluorophenyl) -4-methoxy-3-piperazin-1-ylbenzenesulfonamide (SB-357134).

✍ Steven M. Bromidge; et al. et al. 📂 Article 📅 2001 🏛 John Wiley and Sons ⚖ 36 KB 👁 1 views

Discovery of 1-(3-{2-[4-(2-Methyl-5-quin

Discovery of 1-(3-{2-[4-(2-Methyl-5-quinolinyl)-1-piperazinyl]ethyl}phenyl)-2-imidazolidinone (GSK163090), a Potent, Selective, and Orally Active 5-HT 1A/B/D Receptor Antagonist

✍ Leslie, Colin P.; Biagetti, Matteo; Bison, Silvia; Bromidge, Steven M.; Di Fabio 📂 Article 📅 2010 🏛 American Chemical Society 🌐 English ⚖ 896 KB

6-Chloro-5-methyl-1-[[2-[(2-methyl-3- py

6-Chloro-5-methyl-1-[[2-[(2-methyl-3- pyridyl)oxy]-5-pyridyl]carbamoyl]indoline (SB-242084): The First Selective and Brain Penetrant 5-HT 2C Receptor Antagonist

✍ Bromidge, Steven M.; Duckworth, Malcolm; Forbes, Ian T.; Ham, Peter; King, Frank 📂 Article 📅 1997 🏛 American Chemical Society 🌐 English ⚖ 131 KB

(+)-(2R,5S)-4-[4-Cyano-3-(trifluoromethy

(+)-(2R,5S)-4-[4-Cyano-3-(trifluoromethyl)phenyl]-2,5-dimethyl-N-[6-(trifluoromethyl)pyridin-3- yl]piperazine-1-carboxamide (YM580) as an Orally Potent and Peripherally Selective Nonsteroidal Androgen Receptor Antagonist1

✍ Kinoyama, Isao; Taniguchi, Nobuaki; Toyoshima, Akira; Nozawa, Eisuke; Kamikubo, 📂 Article 📅 2006 🏛 American Chemical Society 🌐 English ⚖ 300 KB

N -[3-(2-Dimethylaminoethyl)-2-methyl-1

N -[3-(2-Dimethylaminoethyl)-2-methyl-1 H - indol-5-yl]-4-fluorobenzamide: A Potent, Selective, and Orally Active 5-HT 1F Receptor Agonist Potentially Useful for Migraine Therapy

✍ Xu, Yao-Chang; Johnson, Kirk W.; Phebus, Lee A.; Cohen, Marlene; Nelson, David L 📂 Article 📅 2001 🏛 American Chemical Society 🌐 English ⚖ 62 KB