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5′-C-branched thymidines: Synthesis, stereochemistry, and incorporation into oligodeoxynucleotides

✍ Scribed by Guangyi Wang; Patrick J. Middleton


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
237 KB
Volume
37
Category
Article
ISSN
0040-4039

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ChemInform Abstract: Synthesis of 5′-C-H
✍ G. WANG; P. J. MIDDLETON; Y.-Z. AN 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 32 KB 👁 2 views

Synthesis of 5'-C-Hydroxyalkylthymidines and Their Incorporation into Oligodeoxynucleotides. -Starting from known thymidine derivatives, title compounds (VII), (IX), and (XI) are prepared. Incorporation may be achieved by conversion to side-chain acetylated phosphoramidites. -(WANG,