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5-Bromo-2'-deoxycytidine (BCDR)-II. Studies with murine neoplastic cells in culture and in vitro

✍ Scribed by John W. Cramer; William H. Prusoff; Arnold D. Welch


Book ID
115767524
Publisher
Elsevier Science
Year
1961
Tongue
English
Weight
429 KB
Volume
8
Category
Article
ISSN
0006-2952

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## Abstract Erythroid differentiation of Friend leukemia cells is enhanced when the cells are grown for four days in the presence of dimethylsulfoxide (DMSO). Dimethylformamide (DMF) has a similar though less marked effect. 5‐Bromo‐2′‐deoxyuridine (BUdR) (10^βˆ’5^M) inhibits both DMF‐ and DMSO‐stimul