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5-Aryl-1,5-dihydro-2H-1,4-benzodiazepin-2-ones

✍ Scribed by Bell, Stanley C.; McCaully, Ronald J.; Childress, Scott J.


Book ID
120994684
Publisher
American Chemical Society
Year
1968
Tongue
English
Weight
327 KB
Volume
11
Category
Article
ISSN
0022-2623

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Solid-phase Friedel–Crafts acylation on
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Friedel-Crafts acylation with various acyl chlorides of resin-bound 3,4-dimethoxyphenylacetate afforded resin bound ketones which, following treatment with hydrazine, were converted into the corresponding 2,3-benzodiazepines in good yields and purities.