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5-[5-(4-Methoxy­phenyl)-3-tri­fluoro­methyl-1H-pyrazol-1-yl]-2-sulfamoyl­benzyl propionate: a novel 1,5-dirayl­pyrazole class of COX-2 inhibitor

✍ Scribed by Vyas, K. ;Sivalakshmidevi, A. ;Singh, S. K. ;Koteswar Rao, Y. ;Om Reddy, G.

Book ID
104481058
Publisher
International Union of Crystallography
Year
2003
Tongue
English
Weight
286 KB
Volume
59
Category
Article
ISSN
1600-5368

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✦ Synopsis

Single-crystal X-ray study T = 298 K Mean '(C±C) = 0.003 A Ê R factor = 0.058 wR factor = 0.088 Data-to-parameter ratio = 11.9

For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.

📜 SIMILAR VOLUMES

4-{(2,4-Dichloro­phen­yl)[5-hydr­oxy-1-p
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The title compound, C 27 H 16 Cl 2 F 6 N 4 O 2 ÁH 2 O, was obtained by the reaction of 2,4-dichlorobenzaldehyde and 2-phenyl-5trifluoromethyl-2H-pyrazol-3-ol in aqueous media without any catalyst. In the crystal structure, both intra-and intermolecular hydrogen bonds are found.

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Single-crystal X-ray study T = 298 K Mean '(C±C) = 0.004 A Ê R factor = 0.055 wR factor = 0.165 Data-to-parameter ratio = 13.7 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.

1-[2,6-Di­chloro-4-(tri­fluoro­methyl)­p
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Single-crystal X-ray study T = 298 K Mean (C±C) = 0.005 A Ê Disorder in main residue R factor = 0.072 wR factor = 0.215 Data-to-parameter ratio = 13.3 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.

N-{3-Cyano-1-[2,6-di­chloro-4-(tri­fluor
N-{3-Cyano-1-[2,6-di­chloro-4-(tri­fluoro­methyl)­phenyl]-1H-pyrazol-5-yl}benz­amide
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The title compound, C 18 H 9 Cl 2 F 3 N 4 O, is a tricyclic amide with an overall U-shape. NÐHÁ Á ÁN hydrogen bonds generate linear chains which extend along the a axis.

N-{3-Cyano-1-[2,6-di­chloro-4-(tri­fluor
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✍ Yang, Zhiping ;Zhong, Ping ;Guo, Shengrong 📂 Article 📅 2004 🏛 International Union of Crystallography 🌐 English ⚖ 273 KB

Single-crystal X-ray study T = 298 K Mean '(C±C) = 0.004 A Ê R factor = 0.064 wR factor = 0.170 Data-to-parameter ratio = 13.2 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.