## Abstract This paper deals with the synthesis of a number of new 4__H__‐thieno[3,4‐__e__] and 4__H__‐pyrazolo[4,3‐__e__]‐1,2,4‐thiadiazine 1,1‐dioxide derivatives 1, the study of their chemical behavior in some alkylation reactions and the evaluation of their vasorelaxant effects on spontaneous m
4H-Thieno[3,4-e]- and 4H-Pyrazolo[4,3-e]-1,2,4-thiadiazine 1,1-Dioxides. Synthesis, Chemical Properties and Evaluation of Their Potential Cardiovascular Activity.
✍ Scribed by Salvador Vega; Maria Esther Arranz
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 119 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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📜 SIMILAR VOLUMES
## Abstract Attempted hydrolysis of the ester of 3‐methoxycarbonyl‐1__H__‐thieno[2,3‐__e__][1,3,4]thiadiazine 4,4‐dioxide (**I**) under acidic conditions gave the ring‐contracted thieno[2,3‐__d__][1,2,3]thiadiazole (**V**) instead of the expected carboxylic acid. In addition to a discussion of the
## Abstract magnified image Two series of 4__H__‐pyrido[4,3‐__e__]‐1,2,4‐thiadiazine derivatives **3**, **4**, **5** and **7**, **8**, **9**, **10**, **11**, **12** were synthesized by the reactions of 3‐methylthiopyrido[4,3‐__e__]‐1,4,2‐dithiazine 1,1‐dioxide **1** with 2‐or 6‐hydrazinoazines and