495 P72R and PIN3 TP53 Polymorphisms and Colorectal Cancer Risk
✍ Scribed by L.P. Oliveira; B.C. Lisboa; I. Lopez; M. Marín; D.M. Carraro; R.A. Coudry
- Book ID
- 117663002
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 56 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0959-8049
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## Abstract A single nucleotide polymorphism (SNP) at codon 72 of the __p53__ gene (Arg72Pro) alters the p53 protein structure and affects its activity. We investigated this SNP in relation to colorectal adenoma and cancer among men and women from case–control studies nested within the Nurses' Heal
## Abstract No clear consensus has been reached on the __TP53__ Arg72Pro polymorphism (G12139C) and lung cancer risk. Thus, a meta‐analysis was conducted to summarize the possible association. There was no statistical association between 12139C (Pro allele) and lung cancer risk in Caucasians compar