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492 High Prevalence of Gastric Cancer in Families with Germline TP53 Mutations

โœ Scribed by Serena Masciari; Akriti Dewanwala; Elena M. Stoffel; Frederick Li; Judy E. Garber; Sapna Syngal

Book ID
119428191
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
87 KB
Volume
134
Category
Article
ISSN
0016-5085

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Mutations in the TP53 gene are considered to be among the most common genetic alterations in human cancers. Both somatic and germline mutations have been found. Using polymerase chain reaction (PCR). constant denaturant gel electrophoresis (CDGE), and denaturing gradient gel electrophoresis (DGGE),