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48 Amplification and overexpression of vinculin are associated with increased tumour cell proliferation and progression in advanced prostate cancer

โœ Scribed by C. Ruiz; D. Holz; M. Oeggerli; S. Schneider; J. Kiefer; I. Gonzales; T. Zellweger; M. Barrett; D. Azorsa; L. Bubendorf


Book ID
119601838
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
47 KB
Volume
8
Category
Article
ISSN
1359-6349

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The tumour growth kinetics (cell proliferation and apoptosis) of ten hormone-refractory locally recurrent prostate cancers were compared with their matched untreated primary tumour specimens. All recurrent tumours had a higher cell proliferation activity, as defined by Ki-67 immunohistochemistry, th