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475 PNPLA3 POLYMORPHISM IN PATIENTS WITH CHRONIC HEPATITIS C – IMPACT ON STEATOSIS, FIBROSIS AND TREATMENT RESPONSE

✍ Scribed by A.F. Stättermayer; K. Rutter; H. Hofer; T.M. Scherzer; S. Beinhardt; P. Steindl-Munda; F. Wrba; M. Trauner; P. Ferenci

Book ID
117379620
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
44 KB
Volume
54
Category
Article
ISSN
0168-8278

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Only 20% of patients with chronic hepatitis C (CHC) will develop cirrhosis, and fibrosis progression remains highly unpredictable. A recent genome-wide association study identified a genetic variant in the patatin-like phospholipase-3 (PNPLA3) gene (rs738409 C>G) associated with steatosis that was f