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124 IMPACT OF PNPLA3 (RS738409 C>G) POLYMORPHISM ON FIBROSIS PROGRESSION AND STEATOSIS IN CHRONIC HEPATITIS C

✍ Scribed by E. Trépo; P. Pradat; A. Potthoff; T. Gustot; A. Lemmers; E. Quertinmont; P. Berthillon; J. Deviére; M. Manns; C. Trépo; H. Wedemeyer; D. Franchimont; C. Moreno

Book ID
117379270
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
42 KB
Volume
54
Category
Article
ISSN
0168-8278

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Impact of patatin-like phospholipase-3 (rs738409 C>G) polymorphism on fibrosis progression and steatosis in chronic hepatitis C
✍ Eric Trépo; Pierre Pradat; Andrej Potthoff; Yukihide Momozawa; Eric Quertinmont; 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 285 KB 👁 1 views

Only 20% of patients with chronic hepatitis C (CHC) will develop cirrhosis, and fibrosis progression remains highly unpredictable. A recent genome-wide association study identified a genetic variant in the patatin-like phospholipase-3 (PNPLA3) gene (rs738409 C>G) associated with steatosis that was f