The synthesis of disodium-3-amino-1-hydr
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Ernest Magnien; Mujahid Shaikh; John T. Suh; Howard Jones
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Article
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1982
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John Wiley and Sons
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French
β 169 KB
## Abstract Disodiumβ3βaminoβ1βhydroxyβ1, 1βdiphosphonateβ1β^14^C (APD 2Na), a powerful calcium binding agent and potential drug for the treatment of Paget's Disease was synthesized. The reaction was carried out by reacting Ξ²βalanine (1β^14^C) with phosphorus acid and phosphorus trichloride in chlo