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456 The effect of inhalation of the leukotriene D4 (LTD4) antagonist SKF 104353 ON LTC4- and LTE4-induced bronchoconstriction in asthmatic subjects

✍ Scribed by CHRISTIE, P; CREA, A; SPUR, B; LEE, T


Book ID
119060638
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
142 KB
Volume
87
Category
Article
ISSN
1097-6825

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The effect of aerosolized SK&F 104353-Z2
✍ G.F. Joos; J.C. Kips; R.A. Pauwels; M.E. Van Der Straeten πŸ“‚ Article πŸ“… 1991 πŸ› Elsevier 🌐 English βš– 494 KB

Leukotriene D4 (LTD4) is a potent bronchoconstrictor and vasoactive mediator that has been implicated in the pathogenesis of bronchial asthma. We have studied the effect of SK&F 104353-Z2, a specific LTD4 antagonist, on LTD4-induced bronchoconstriction in asthmatics. A total of 12 mild asthmatics (m