4(5)-Nitro-1H-imidazole-5(4)-carbonitriles. Synthesis by cine-substitution reactions
✍ Scribed by Jerzy Suwiński; Krzysztof Świerczek
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- French
- Weight
- 124 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
The first syntheses of 4(5)-nitro-IH-imidazole-5(4)-carbonitrile, its 2-methyl derivative and salts of both compounds with DBU have been described. The carbonitriles have been obtained by a treatment of 1,4-dinitroimidazoles with potassium cyanide in aqueous methanol solution.
📜 SIMILAR VOLUMES
## Abstract __Cine__ nucleophilic substitution of 1,4‐dinitroimidazole and its 2‐methyl derivative with nitrogen‐15 or carbon‐13 potassium cyanides afforded, respectively, labelled 4(5)‐nitro‐1H‐imidazole‐5(4)‐carbonitriles. Detailed mass spectra analysis led to the conclusion that during fragmenta
Synthesis of Substituted 2-Amino-5-nitro-4H-pyran-3-carbonitriles. -The reaction of α-nitroketone (I) with benzylidenemalononitriles (II) catalyzed by Et 3 N represents the first example of a synthesis of nitropyrans (III) from α-nitroketones.