Identifying stabilizers of plasmid DNA f
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Yuhong Zeng; Joshua D. Ramsey; Robert King; Michael Leviten; Ruth Mcguire; David
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Article
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2011
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John Wiley and Sons
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English
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To better address the need for developing stable formulations of plasmid DNA-based biopharmaceuticals, 37 compounds from a generally regarded as safe library were examined for their potential use as stabilizers. A plasmid DNA-based therapeutic vaccine, BHT-DNA, was used as a model system. Initial st