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4,4-Difluoro-1α,25-dihydroxyvitamin D3: Analog to probe A-ring conformation in vitamin D-receptor complex

✍ Scribed by Masato Shimizu; Yukiko Iwasaki; Sachiko Yamada

Book ID: 104260828
Publisher: Elsevier Science
Year: 1999
Tongue: French
Weight: 234 KB
Volume: 40
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(99)00030-1

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✦ Synopsis

4,4-Difluoro-ltx,25-dihydroxyvitamin D 3 was synthesized from ergosterol and analysis of its 19F NMR showed it to be a useful probe to analyze the receptor-bound A-ring conformation of vitamin D.

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