Hepatocellular adenomas (HCA) with activated beta-catenin present a high risk of malignant transformation. To permit robust routine diagnosis to allow for HCA subtype classification, we searched new useful markers. We analyzed the expression of candidate genes by quantitative reverse transcription p
[43] SUBTYPE CLASSIFICATION OF HEPATOCELLULAR ADENOMAS BY MOLECULAR MARKERS AND IMMUNOHISTOCHEMISTRY
β Scribed by P. Bioulac-Sage; S. Rebouissou; C. Thomas; J.F. Blanc; J. Saric; E. Jeannot; A. Sa Cunha; G. Couchy; S. Imbeaud; C. Balabaud; J. Zucman-Rossi
- Book ID
- 117375145
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 145 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0168-8278
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Hepatocellular adenomas (HCAs) are a group of benign tumors forming three molecular pathological subgroups: (1) hepatocyte nuclear factor 1β£ (HNF-1β£)-inactivated, (2) β€-catenin-activated, and (3) inflammatory. Some HCAs present both β€-catenin activation and inflammation. We analyzed magnetic resonan