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425 POSTER Biological role of the CREB/COX-2 pathway in the regulation of human pancreatic cancer proliferation and survival

✍ Scribed by M.S. Pino; M. Milella; A. Gelibter; A. Felici; F. Cognetti; D.J. McConkey


Book ID
118624053
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
62 KB
Volume
4
Category
Article
ISSN
1359-6349

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Enterovirus 71 modulates a COX-2/PGE2/cA
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## Abstract Enterovirus 71 (EV71) has been shown to induce cyclooxygenase‐2 (COX‐2) expression in human neuroblastoma SK‐N‐SH cells through the action of MAPKs, NF‐κB, and AP‐1. On the other hand, the transcription factor CREB has also been implicated in the expression of COX‐2 in other cell lines.