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416 IMPACT OF COMBINED HDAC AND MTOR INHIBITION ON THE INVASIVE POTENTIAL OF PROSTATE CANCER CELLS

✍ Scribed by Wedel, Steffen; Hudak, Lucasz; Makarevic, Jasmina; Seibel, Jens-Michael; Juengel, Eva; Haferkamp, Axel; Blaheta, Roman


Book ID
122358577
Publisher
Lippincott Williams and Wilkins
Year
2011
Tongue
English
Weight
43 KB
Volume
185
Category
Article
ISSN
0022-5347

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Phenylbutyrate inhibits the invasive pro
✍ Erica S. Dyer; Michelle T. Paulsen; Sonja M. Markwart; Meidee Goh; Donna L. Liva πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 French βš– 98 KB

## Abstract Histone deacetylase inhibitors, such as phenylbutyrate, are currently undergoing clinical trials as potential anticancer agents. Phenylbutyrate can induce cell differentiation and apoptosis in a number of cancer cell types and can act in synergy with ionizing radiation and chemotherapy