𝔖 Bobbio Scriptorium
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41. The ras oncogene as a therapeutic target

✍ Scribed by Wood, AW


Book ID
122941486
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
115 KB
Volume
46
Category
Article
ISSN
0753-3322

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The NF1 gene encodes neurofibromin, a GTPase-activating protein (GAP) for members of the p21 ras (Ras) family, which negatively regulates Ras output by accelerating the conversion of active RasΠΈGTP to inactive RasΠΈGDP. Analysis of tumors from patients with neurofibromatosis type 1 (NF1) has shown bi