The NF1 gene encodes neurofibromin, a GTPase-activating protein (GAP) for members of the p21 ras (Ras) family, which negatively regulates Ras output by accelerating the conversion of active RasΠΈGTP to inactive RasΠΈGDP. Analysis of tumors from patients with neurofibromatosis type 1 (NF1) has shown bi
β¦ LIBER β¦
ChemInform Abstract: Ras Farnesyltransferase: A New Therapeutic Target
β Scribed by D. M. LEONARD
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 24 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0931-7597
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