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41 HER2-expression in advanced ovarian cancer: A prognostic and predictive marker? An study of the AGO ovarian study group

✍ Scribed by H.J. Lück; F. Kommoss; E. Riener; N. Arnold; H.P. Adams; F. Hilpert; A. Du Bois; J. Pfisterer


Book ID
118620217
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
323 KB
Volume
1
Category
Article
ISSN
1359-6349

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## Abstract ## BACKGROUND The HER‐2 (Human Epidermal Growth factor receptor‐2, also known as c‐__erb__‐2/__neu__) protooncogene encodes a transmembrane receptor protein, __M__~r~ 185,000. Studies have shown that the HER‐2 oncogene is overexpressed in approximately 25–30% of ovarian carcinoma (OC)