RETRACTED: The prognostic and predictive value of immunohistochemically detected HER-2/neu overexpression in 361 patients with ovarian cancer: a multicenter study
β Scribed by Eva-Katrin Riener; Norbert Arnold; Friedrich Kommoss; Stefan Lauinger; Jacobus Pfisterer
- Book ID
- 113959439
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 145 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0090-8258
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## Abstract ## BACKGROUND The HERβ2 (Human Epidermal Growth factor receptorβ2, also known as cβ__erb__β2/__neu__) protooncogene encodes a transmembrane receptor protein, __M__~r~ 185,000. Studies have shown that the HERβ2 oncogene is overexpressed in approximately 25β30% of ovarian carcinoma (OC)
## Abstract Our study attempts to determine the prognostic value of the quantitative measurement of the oncoprotein p185^Herβ2/neu^ in a group of patients with breast cancer and positive node involvement. In a series of 217 patients with breast cancer and positive nodes in whom the oncoprotein p185