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41-5 - Transdermal delivery of xanomeline, and M1/M4 agonist in development for the treatment of Alzheimer's disease

โœ Scribed by N.C. Bodick; R. Lucas; J.H. Satterwhite; W.W. Offen


Book ID
118511876
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
429 KB
Volume
42
Category
Article
ISSN
0006-3223

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Xanomeline: A selective muscarinic agoni
โœ Frank P. Bymaster; Celia A. Whitesitt; Harlan E. Shannon; Neil DeLapp; John S. W ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 147 KB ๐Ÿ‘ 3 views

Xanomeline is a novel muscarinic receptor agonist relatively devoid of parasympathomimetic side effects. Xanomeline had high affinity for muscarinic receptors and much lower affinity for a variety of other neuronal receptors in radioligand binding assays. Functional studies in cell lines transfected