In vivo drug target discovery: identifyi
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D.Wade Walke; Chunsheng Han; Joseph Shaw; Elisabeth Wann; Brian Zambrowicz; Arth
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Article
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2001
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Elsevier Science
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English
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A vast number of genes of unknown function threaten to clog drug discovery pipelines. To develop therapeutic products from novel genomic targets, it will be necessary to correlate biology with gene sequence information. Industrialized mouse reverse genetics is being used to determine gene function i