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4-Substituted 1-(2-methylphenyl)thieno[2,3-c]-1,5-naphthyridines as possible reversible inhibitors of gastric H+,K+-ATPase

✍ Scribed by P Björk; A.B. Hörnfeldt; S Gronowitz; U Edvardsson

Book ID
103630136
Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
576 KB
Volume
31
Category
Article
ISSN
0223-5234

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Chemoselective Synthesis of Thieno[3,2-c
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✍ Majumdar Krishna C. Majumdar Krishna C.; Rafique-ul-Islam Rafique-ul-Islam 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 24 KB 👁 1 views

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Chemoselective synthesis of thieno[3,2-c
Chemoselective synthesis of thieno[3,2-c][1,8]naphthyridin-4(5H)-ones by tandem cyclization
✍ Krishna C. Majumdar; Rafique-ul-Islam 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 127 KB 👁 1 views

## Abstract A number of the thieno[3,2‐__c__][1,8]‐naphthyridin‐4(5__H__)‐ones are chemoselectively synthesized from 4‐(4′‐aryloxybut‐2′‐ynylthio)‐1‐phenyl‐1,8‐naphthyridin‐2(1__H__)‐ones in 82–90% yield by the formation of sulfoxide, followed by [2,3] and [3,3]sigmatropic rearrangement and an intr