**Die bisher kürzeste und effektivste Phytosphingosin‐Synthese** gelang nach einem Konzept, nach dem verschiedene Aminozucker einfach ”︁zusammengebaut„ werden können. Die beiden entscheidenden Schritte bei der Herstellung der Titelverbindung __(3)__, die hochstereoselektiv verlaufen, sind die Hydrox
✦ LIBER ✦
4-Hydroxylation of Isoxazolines; Synthesis of rac-Phytosphingosine (ribo-2-Amino-1,3,4-octadecanetriol)
✍ Scribed by Dr. Wilfried Schwab; Prof. Dr. Volker Jäger
- Publisher
- John Wiley and Sons
- Year
- 1981
- Tongue
- English
- Weight
- 382 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0044-8249
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A series of 4-(alkylidene/arylidene)amino-5-(2-furanyl)-2.4-dihydro-3H-I .2.4-triazolc-3-1hiones (2) and 6-aryl-3-(2-furanyl)-7H-12.4-triazolo[3,4-b]( 1.3.41 thiadiazines (3) werc synthesized. The configuration of 2g was assigned on che basis of 'H-NMR data. Of the new derivatives tesced. only 2b. 2