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4-Hydroxy-2-nonenal, the End Product of Lipid Peroxidation, Is a Specific Inducer of Cyclooxygenase-2 Gene Expression

✍ Scribed by Takeshi Kumagai; Yoshiyuki Kawamoto; Yoshimasa Nakamura; Ichiro Hatayama; Kimihiko Satoh; Toshihiko Osawa; Koji Uchida


Book ID
115586051
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
126 KB
Volume
273
Category
Article
ISSN
0006-291X

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πŸ“œ SIMILAR VOLUMES


Synthesis of the lipid peroxidation prod
✍ I. Jouanin; V. Sreevani; E. Rathahao; F. GuΓ©raud; A. Paris πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 French βš– 200 KB

## Abstract The aim of this work was to synthesize ^13^C internal standards for the quantification of 4‐hydroxy‐2(E)‐nonenal (HNE), a lipid peroxidation product, and of the etheno‐adducts possibly formed by HNE damage to DNA nucleobases. We designed an eight‐step synthesis starting from ethyl 2‐bro