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4'-Fluoro-4-[4-(2-pyridyl)-1-piperazinyl]butyrophenone (azaperone)

✍ Scribed by Koch, M. H. J. ;Germain, G. ;Declercq, J. P. ;Van Meerssche, M.

Book ID
114524266
Publisher
International Union of Crystallography
Year
1977
Weight
165 KB
Volume
33
Category
Article
ISSN
0567-7408

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Labelling of neuroleptic butyrophenones. III. Synthesis of 2′-amino-4′-fluoro-4-[4-hydroxy-4-(3-trifluoromethylphenyl)piperidino-2-14C] - butyrophenone
✍ Iwao Nakatsuka; Kazuo Kawahara; Akira Yoshitake 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 French ⚖ 474 KB

## Abstract 2′‐Amino‐4′ ‐fluoro‐4‐(4‐hydroxy‐4‐) (3‐trifluoromethylphenyl) ‐ piperidino‐2‐^14^Cbutyrophenone [ID‐4708‐ (piperidine‐^14^C]), a neuroleptic agent, was synthesized for use in metabolic studies. The synthesis was achieved by the reaction scheme shown in Fig. 1. 1‐Benzyl‐4‐piperidone‐2‐^