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4-deoxyannomontacin and (2,4-cis and trans)-annomontacinone, new bioactive mono-tetrahydrofuran annonaceous acetogenins from Goniothalamus giganteus

✍ Scribed by Feras Alali; Lu Zeng; Yan Zhang; Qing Ye; D. Craig Hopp; Jon T. Schwedler; Jerry L. McLaughlin


Book ID
108480554
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
624 KB
Volume
5
Category
Article
ISSN
0968-0896

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By bioactivity-directed fractionation using lethality to brine shrimp, two new bioactive ketolactone Annonaceous acetogenins, 2,4-cis-and 2,4-trans-venezinones (1 and 2), were isolated as a mixture from the 95% ethanol extract of the bark of Xylopia aromatica (Annonaceae). Compounds 1 and 2 represen