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(2,4- cis and trans )-Gigantecinone and 4-Deoxygigantecin, Bioactive Nonadjacent Bis-Tetrahydrofuran Annonaceous Acetogenins, from Goniothalamus giganteus

✍ Scribed by Alali, Feras Q.; Zhang, Yan; Rogers, Lingling; McLaughlin, J. L.


Book ID
120586581
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
138 KB
Volume
60
Category
Article
ISSN
0163-3864

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By bioactivity-directed fractionation using lethality to brine shrimp, two new bioactive ketolactone Annonaceous acetogenins, 2,4-cis-and 2,4-trans-venezinones (1 and 2), were isolated as a mixture from the 95% ethanol extract of the bark of Xylopia aromatica (Annonaceae). Compounds 1 and 2 represen