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4-Bromocrotonic Acid Enhances Basal but Inhibits Insulin-Stimulated Glucose Transport in 3T3-L1 Adipocytes

✍ Scribed by Shr-Jen Leu; Shin-Pei Chai; Ching Fai Kwok; Jim C. Fong

Book ID
115581708
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
129 KB
Volume
244
Category
Article
ISSN
0006-291X

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πŸ“œ SIMILAR VOLUMES

Nigericin inhibits insulin-stimulated gl
Nigericin inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes
✍ Chih-Ying Chu; Ying-Shun Kao; Jim C. Fong πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 187 KB

## Abstract We used nigericin, a K^+^/H^+^ exchanger, to test whether glucose transport in 3T3‐L1 adipocytes was modulated by changes in intracellular pH. Our results showed that nigericin increased basal but decreased insulin‐stimulated glucose uptake in a time‐ and dose‐dependent manner. Whereas