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4-(2-Furyl)-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-d]pyrimidine

✍ Scribed by Brændvang, Morten ;Gundersen, Lise-Lotte

Publisher
International Union of Crystallography
Year
2007
Tongue
English
Weight
971 KB
Volume
63
Category
Article
ISSN
1600-5368

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✦ Synopsis

The title compound, C 17 H 14 N 4 O 2 , is a close analog of potent antimycobacterial purines. Molecules are linked by C-HÁ Á ÁN hydrogen bonds, forming infinite chains along [010]. The secondary structure is further stabilized by weak intermolecular contacts of types C-HÁ Á ÁN and C-HÁ Á ÁO.

Related literature

Most bond lengths and angles are in good agreement with those found for 6-furyl-and 6-thienyl-9-benzylpurines (Braendvang & Gundersen, 2007a;Mazumdar et al., 2001), except that the furyl ring in the title compound is rotated by approximately 180 . This orientation of the furyl ring is stabilized by C-HÁ Á ÁO hydrogen bonding.

📜 SIMILAR VOLUMES

ChemInform Abstract: Synthesis of 4-Subs
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✍ M. L. TAHA; H. B. LAZREK 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 31 KB 👁 1 views

Synthesis of 4-Substituted 1-((2,3-Dihydroxy-1-propoxy)methyl)-1Hpyrazolo (3,4-d)pyrimidines. -The regioselective synthesis of a series of acyclonucleosides of pyrazolopyrimidines (cf. (IV), (V), (VII), (IX)) is described. The obtained compounds are evaluated for their cytotoxicity and anti-HIV act

Methyl (4-oxo-1-phenyl-4,5-dihydro-1H-py
Methyl (4-oxo-1-phenyl-4,5-dihydro-1H-pyrazolo[3,4-d]pyrimidin-5-yl)acetate
✍ Yathirajan, H. S. ;Bindya, S. ;Sarojini, B. K. ;Narayana, B. ;Bolte, Michael 📂 Article 📅 2007 🏛 International Union of Crystallography 🌐 English ⚖ 501 KB

The title compound, C 14 H 12 N 4 O 3 , a pyrazolopyrimidine derivative, displays normal geometrical parameters. The dihedral angle between the mean planes of the pyrazolopyrimidine unit and the phenyl ring is 26.14 (4) . The non-H atoms of the ester side chain are coplanar (r.m.s. deviation = 0.009

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Ethyl (4-oxo-1-phenyl-1,4-dihydro-5H-pyrazolo[3,4-d]pyrimidin-5-yl)acetate
✍ Yathirajan, H. S. ;Bindya, S. ;Sarojini, B. K. ;Narayana, B. ;Bolte, Michael 📂 Article 📅 2007 🏛 International Union of Crystallography 🌐 English ⚖ 372 KB

Geometric parameters of the title compound, C 14 H 12 N 4 O 3 , a pyrazolopyrimidine derivative, are in the usual ranges. The dihedral angle between the pyrazolopyrimidine system and the phenyl ring is 4.64 (5) . The non-H atoms of the ester side chain lie in a common plane (r.m.s. deviation = 0.028

3-(2-Furyl)-4-(4-methoxy­phenyl)-1H-1,2,
3-(2-Furyl)-4-(4-methoxy­phenyl)-1H-1,2,4-triazole-5(4H)-thione
✍ Yıldırım, Sema Öztürk ;Akkurt, Mehmet ;Koparır, Metin ;Cansız, Ahmet ;Şekerci, M 📂 Article 📅 2004 🏛 International Union of Crystallography 🌐 English ⚖ 260 KB

Single-crystal X-ray study T = 100 K Mean '(C±C) = 0.002 A Ê R factor = 0.036 wR factor = 0.084 Data-to-parameter ratio = 15.4 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.