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[4 + 1] Cycloaddition of N-Heterocyclic Carbenes with Vinyl Isocyanates

✍ Scribed by Rigby, James H.; Wang, Zhengqiang


Book ID
121087957
Publisher
American Chemical Society
Year
2002
Tongue
English
Weight
53 KB
Volume
4
Category
Article
ISSN
1523-7060

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πŸ“œ SIMILAR VOLUMES


Asymmetric induction in [1+4] cycloaddit
✍ James H. Rigby; Alexandre Cavezza; Mary Jane Heeg πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 French βš– 214 KB

Several chirally-modified nucleophilic carbenes afford useful levels of asymmetric induction during [1+4] cycloaddition with vinyl isocyanate reaction partners. Carbenes derived from the 1,2-aminoalcohols (1R,2S)-ephedrine and (1R,2S)-methylaminoindanol proved to be the most effective for delivering