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[3H]methylcarbamylcholine, a new radioligand for studying brain nicotinic receptors

✍ Scribed by Leo G. Abood; Susan Grassi

Book ID
115779307
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
310 KB
Volume
35
Category
Article
ISSN
0006-2952

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## Abstract Imidacloprid is an exceptionally potent insecticide known from physiological studies to act at the nicotinic acetylcholine receptor. To prepare [^3^H]imidacloprid as a candidate radioligand, 6‐chloronicotinoyl chloride was reduced with NaB^2^H~4~ (in model studies) or NaB^3^H~4~ in abso