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[3H]benzylpempidine, a new radioligand for probing a putative channel site on nicotinic cholinergic receptors

✍ Scribed by David X. Wang; Shey-Shing Sheu; Virendra K. Sharma; Lisa Rubin; Michel Journet; Andrew S. Kende; Leo G. Abood

Book ID
117174932
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
528 KB
Volume
60
Category
Article
ISSN
0024-3205

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## Abstract Reaction of glutarimide with pent‐4‐enylmagnesium bromide, followed by cyclization of intermediate ketoamide, and hydrolysis of the formates **10** and **13** led to the mixture of the hydroxylactams **11** __(cis)__ and **14** __(trans)__ which could be separated __via__ their benzenec