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[3H]cyclofoxy, a ligand suitable for positron emission tomography, labels mu and kappa opioid receptors

โœ Scribed by Stafford McLean; Kennner C. Rice; Ralph Lessor; Richard B. Rothman


Book ID
119073674
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
758 KB
Volume
10
Category
Article
ISSN
0143-4179

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## Abstract Iodobenzamide (IMB) labeled with either [^11^C] or [^125^I] was studied in mice and baboons. Pharmacological studies demonstrated an in vivo binding profile compatible with D~2~ dopamine receptors. Mouse biodistribution studies with both [^11^C]IMB and [^125^I]IMB showed a similar brain