✦ LIBER ✦

[3H]-F13640, a novel, selective and high-efficacy serotonin 5-HT1Areceptor agonist radioligand

✍ Scribed by Peter Heusler; Christiane Palmier; Stéphanie Tardif; Sophie Bernois; Francis C. Colpaert; Didier Cussac

Publisher: Springer-Verlag
Year: 2010
Tongue: English
Weight: 364 KB
Volume: 382
Category: Article
ISSN: 0028-1298
DOI: 10.1007/s00210-010-0551-4

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Labelling of recombinant human and nativ

Labelling of recombinant human and native rat serotonin 5-HT1A receptors by a novel, selective radioligand, [3H]-S 15535: Definition of its binding profile using agonists, antagonists and inverse agonists

✍ A. Newman-Tancredi; L. Verrièle; C. Chaput; M. J. Millan 📂 Article 📅 1998 🏛 Springer-Verlag 🌐 English ⚖ 146 KB

Synthesis and in vivo evaluation of a no

Synthesis and in vivo evaluation of a novel 5-HT1Areceptor agonist radioligand [O-methyl-11C]2-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-4-methyl-1,2,4-triazine-3,5(2H,4H)dione in nonhuman primates

✍ J. S. Dileep Kumar; Jaya Prabhakaran; Vattoly J. Majo; Matthew S. Milak; Shu-Chi 📂 Article 📅 2007 🏛 Springer 🌐 English ⚖ 363 KB

Novel 6,7,8,9-tetrahydro-5H-1,4,7,10a-te

Novel 6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene analogues as potent and selective 5-HT2C agonists for the treatment of metabolic disorders

✍ Heather Tye; Stephan G. Mueller; Juergen Prestle; Stefan Scheuerer; Marcus Schin 📂 Article 📅 2011 🏛 Elsevier Science 🌐 English ⚖ 338 KB

The discovery of a novel series of 5-HT(2C) agonists based on a tricyclic pyrazolopyrimidine scaffold is described. Compounds with good levels of in vitro potency and moderate to good levels of selectivity with respect to the 5-HT(2A) and 5-HT(2B) receptors were identified. One of the analogues (7 g