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378 - Generation and characterization of cytotoxic T lymphocytes (CTL) against mutated ras peptides

✍ Scribed by A. Juretic; M. Samija; D. Eljuga; M. Turic; M. Heberer; G.C. Spagnoli


Book ID
117664633
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
264 KB
Volume
33
Category
Article
ISSN
0959-8049

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Generation of cytotoxic-T-lymphocyte (CTL) responses against mutated ras peptides from peripheral-blood mononuclear cells (PBMC) was attempted in a group of HIA-A2.I+ healthy donors. Bulk PBMC cultures were stimulated in vitro with a mixture of peptides encompassing I 2 Gly + Val, 6 I Gln + Lys or 6