Generation and characterization of peptide-specific, MHC-restricted cytotoxic T lymphocyte (CTL) and helper T cell lines from unprimed T cells under microculture conditions

Generation of RAGE-1 and MAGE-9 peptide-

Generation of RAGE-1 and MAGE-9 peptide-specific cytotoxic T-Lymphocyte lines for transfer in patients with renal cell carcinoma

✍ Nicole Oehlrich; Gerard Devitt; Michael Linnebacher; Yvette Schwitalle; Sonja Gr 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 French ⚖ 342 KB

## Abstract Renal cell carcinomas (RCCs) are supposed to be immunogenic, and several clinical trials of immunotherapy using tumor lysate‐pulsed dendritic cells (DCs) have been performed. We report on the generation of RAGE‐1 and MAGE‐9 peptide‐specific CTL lines. RAGE‐1 and MAGE‐9 are expressed in