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36 Plasminogen activator inhibitor type-1 inhibits integrin- and vitronectin-dependent cell migration

✍ Scribed by L. Kjøller; S.M. Kanse; T. Kirkegaard; K.W. Rodenburg; E. Rønne; S.L. Goodman; K.T. Preissner; L. Ossowski; P.A. Andreasen


Book ID
117439413
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
134 KB
Volume
11
Category
Article
ISSN
0268-9499

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TYPE-1 PLASMINOGEN ACTIVATOR INHIBITOR I
✍ WAGNER, STEPHAN N.; ATKINSON, MICHAEL J.; THANNER, STEPHANIE; SCHMITT, MANFRED; 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 597 KB

In experimental models, plasminogen activator-mediated degradation of the extracellular matrix is inhibited by type-1 plasminogen activator inhibitor (PAI-1). PA14 has also been shown to protect tumour stromal tissue from autoproteolytic activities and may thus substantially promote tumour growth an