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35: Histone deacetylase inhibitors induce indoleamine 2, 3-dioxygenase and modulate dendritic cell functions

✍ Scribed by P. Reddy; Y. Sun; Y. Maeda; E. Weisiger; R. Duran-Struuck; C. Dinarello; J.L. Ferrara

Book ID: 116279216
Publisher: Elsevier Science
Year: 2007
Tongue: English
Weight: 65 KB
Volume: 13
Category: Article
ISSN: 1083-8791
DOI: 10.1016/j.bbmt.2006.12.038

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## Abstract ## Objective We have demonstrated previously that dendritic cells (DCs) modified with immunosuppressive cytokines, and exosomes derived from DCs can suppress the onset of murine collagen‐induced arthritis (CIA) and reduce the severity of established arthritis. Indoleamine 2,3‐dioxygena