Amino-athylantinol-benzoesauremethylestcr (V) In eine iibersohiissiges Diazomethan enthaltende iitherische Losung werden portionsweise 3,8 g (20 mMol) IV eingetragen, das unter Stickstoffentwicklung in Losung geht. Man laat das Reaktionsgemisch 1 2 Stdn. bei Raumtemperatur stehen, filtriert und duns
3,4,5-Trimethyl-1,2,4-triazole trihydrate
✍ Scribed by Beitelman, Adam D. ;Sieracki, Nathan A. ;Zeller, Matthias ;Ferrence, Gregory M.
- Publisher
- International Union of Crystallography
- Year
- 2007
- Tongue
- English
- Weight
- 407 KB
- Volume
- 63
- Category
- Article
- ISSN
- 1600-5368
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Herein we report an approach to the formation of 5-alkynyl-1,3-dioxin-4-ones using Suzuki-Miyaura cross-coupling reaction of potassium alkynyltrifluoroborate salts with 2,2,6-trimethyl-5-iodo-1,3dioxin-4-one. The resulting 5-ethynyltrimethylsilyl-1,3-dioxin-4-ones obtained through the Sonogashira re
In the molecule of the title compound, C 5 H 7 N 7 S, the essentially planar triazole ring and the 4-amino-5-mercapto-1,2,4-triazole moiety make a dihedral angle of 70.97 (5) . In the crystal structure, weak intermolecular N-HÁ Á ÁN and N-HÁ Á ÁS hydrogen bonds stabilize the packing.
## Abstract Optimized conditions are applied to the Suzuki—Miyaura cross‐coupling of potassium alkynyl trifluoroborates with the iodinated 1,3‐dioxin‐4‐one (I).
The two pyridine rings in the title compound, C 12 H 10 N 6 , form dihedral angles of 35.7 (2) and 16.8 (2) with the central triazole ring. The molecules exist as centrosymmetrically related dimers and form a three-dimensional network through intermolecular NÐHÁ Á ÁN hydrogen bonds.