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34-OR: Cytotoxic T lymphocytes of breast cancer survivors recognize novel epitopes presented by the HLA-A*0201

✍ Scribed by Oriana Hawkins; Rodney VanGundy; Annette Eckerd; Wilfried Bardet; Rico Buchli; Jon Weidanz; William Hildebrand


Book ID
116532098
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
48 KB
Volume
69
Category
Article
ISSN
0198-8859

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Mutant p21-ras proteins contain sequences that distinguish them from normal ras, and represent unique epitopes for T-cell recognition of antigen-bearing tumour cells. Here, we examined the capacity of CD4 Ψ‰ and CD8 Ψ‰ T cells, generated simultaneously by mutant-ras-peptide vaccination of a pancreatic