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3,4-Diaminopyridine improves neuromuscular transmission in a MuSK antibody-induced mouse model of myasthenia gravis

✍ Scribed by Shuuichi Mori; Masahiko Kishi; Sachiho Kubo; Takuyu Akiyoshi; Shigeru Yamada; Tsuyoshi Miyazaki; Tetsuro Konishi; Naoki Maruyama; Kazuhiro Shigemoto


Book ID
113730967
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
305 KB
Volume
245
Category
Article
ISSN
0165-5728

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πŸ“œ SIMILAR VOLUMES


Improvement in Neuromuscular transmissio
✍ H. Lundh; O. Nilsson; I. RosΓ©n πŸ“‚ Article πŸ“… 1985 πŸ› Springer-Verlag 🌐 English βš– 361 KB

3,4-Diaminopyridine ( 3,4-DAP), a potent potentiator of action potential evoked release of acetylcholine from presynaptic terminals in the neuromuscular junction was given i v and p o to two patients with myasthenia gravis. Effects were monitored electrophysiologically by repetitive nerve stimulatio