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320 PUBLICATION High frequency of population-specific mutations of BRCA genes among breast cancer patients in the Czech Republic


Book ID
118622900
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
146 KB
Volume
3
Category
Article
ISSN
1359-6349

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## Abstract Breast cancer occurs rarely in men and risk factors for the disease include germline mutations of the __BRCA2__ gene. High frequency of allelic loss at the __BRCA2__ locus has been reported in sporadic breast tumors, but somatic mutations of __BRCA2__ are very rare. Here we report the f