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320 Identification of potent, selective, soluble and permeable small molecule PI3 kinase inhibitors for the treatment of cancer

✍ Scribed by K. Ahmadi; W. Alderton; I. Chuckowree; P. Depledge; A. Folkes; G. Pergl-Wilson; N. Saghir; S. Shuttleworth; N. Wan; F. Raynaud; N.S.S. Saghir; N.C. Wan; A. Zhyvoloup


Book ID
118621503
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
283 KB
Volume
2
Category
Article
ISSN
1359-6349

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Small molecule tyrosine kinase inhibitor
✍ Maninder Sidhu; Carmen Alonso Cotoner; Bayasi Guleng; Seiji Arihiro; Sunyoung Ch πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 774 KB

## Background: We developed a series of dendritic cell autoimmune modulators (DCAMs) based on small molecule Flt3 receptor tyrosine kinase inhibitors (TKIs) for the inhibition of intestinal inflammation and oral delivery. Methods: DCAMs were administered orally during and after induction of dextr