[3+2] Dipolar cycloadditions of an unstabilised azomethine ylide under continuous flow conditions
β Scribed by Mark Grafton; Andrew C. Mansfield; M. Jonathan Fray
- Book ID
- 104097274
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- French
- Weight
- 343 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Lewis base catalysed 1,3-dipolar cycloaddition between Ξ±,Ξ²-unsaturated acyl fluorides and N-[(trimethylsilyl)methyl]amino ethers has been achieved using 1 mol% DMAP. Competition experiments and (19)F-NMR studies indicate that the cycloaddition occurs preferentially between the Ξ±,Ξ²-unsaturated acyl f
A facile one-pot synthesis of novel steroidal dispiropyrrolidines has been accomplished by 1,3-dipolar cycloaddition reaction of various azomethine ylides derived from isatin/acenaphthenequinone/ninhydrin and sarcosine with various estrone derivatives as dipolarophiles, in good yield. The effect of