302 Effects of caffeine on induction of apoptosis in blood monocyte and alveolar macrophage cells
β Scribed by M. Jafari; A. Rabbani
- Book ID
- 119538071
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 54 KB
- Volume
- 144
- Category
- Article
- ISSN
- 0378-4274
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The chemiluminescence of peripheral blood monocytes and alveolar macrophages was determined in the presence of luminol and lucigenin, either before or after the cell adherence to the luminometer curvettes. In the case of monocytes, cell adherence induces an increase of luminol-dependent chemilumines
In this study, the effect of two concentration ranges of the cAMP phosphodiesterase inhibitor, caffeine, on alveolar macrophage function was investigated by measuring survival rate, superoxide anion production and DNA fragmentation. The results show caffeine induced apoptosis in alveolar macrophages